Cell Senescence Entries for SMC2
- Cell Types
- Retinal pigment epithelial
- Cell Lines
- RPE-1
- Cancer Cell?
- No
- Method
- Knockdown
- Type of senescence
- Unclear
- Senescence Effect
- Inhibits
- Primary Reference
- Nishide et al. (2016) Overlapping and non-overlapping functions of condensins I and II in neural stem cell divisions. PLoS Genet 10(12)e1004847 (PubMed)
SMC2 Gene Information
- HGNC symbol
- SMC2
- Aliases
- CAP-E; hCAP-E; SMC2L1
- Common name
- structural maintenance of chromosomes 2
- Entrez Id
- 10592
- Description
SMC2 Ontologies
- Gene Ontology
-
Process: GO:7049; cell cycle
GO:51301; cell division
GO:10032; meiotic chromosome condensation
GO:30261; chromosome condensation
GO:45132; meiotic chromosome segregation
GO:51276; chromosome organization
GO:51383; kinetochore organization
GO:51984; positive regulation of chromosome segregation
GO:1905820; positive regulation of chromosome separation
GO:7076; mitotic chromosome condensation
GO:1905821; positive regulation of chromosome condensation
And 1 more GO terms Cellular component: GO:5634; nucleus
GO:5737; cytoplasm
GO:5654; nucleoplasm
GO:5730; nucleolus
GO:5694; chromosome
GO:793; condensed chromosome
GO:794; condensed nuclear chromosome
GO:796; condensin complex
GO:228; nuclear chromosome
GO:5829; cytosol
GO:70062; extracellular exosome
And 2 more GO terms
Show all GO termsFunction: GO:166; nucleotide binding
GO:5524; ATP binding
GO:5515; protein binding
GO:3682; chromatin binding
GO:3697; single-stranded DNA binding
GO:16887; ATP hydrolysis activity
Homologs of SMC2 in Model Organisms
- Caenorhabditis elegans
- mix-1
- Danio rerio
- smc2
- Drosophila melanogaster
- SMC2
- Mus musculus
- Smc2
- Rattus norvegicus
- Smc2
- Saccharomyces cerevisiae
- SMC2
- Schizosaccharomyces pombe
- cut14
In other databases
- CellAge gene expression
- This gene is present as SMC2
External links
- OMIM
- 605576
- Ensembl
- ENSG00000136824
- Entrez Gene
- 10592
- UniGene
- 119023
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- SMC2
- GeneCards
- SMC2