Cell Senescence Entries for YPEL3
- Cell Types
- Breast cancer
- Cell Lines
- MCF-7
- Cancer Cell?
- Yes
- Method
- Knockdown, Overexpression
- Type of senescence
- Stress-induced
- Senescence Effect
- Induces
- Primary Reference
- Tuttle et al. (2012) Novel senescence associated gene, YPEL3, is repressed by estrogen in ER+ mammary tumor cells and required for tamoxifen-induced cellular senescence. Int J Cancer 130(10)2291-9 (PubMed)
YPEL3 Gene Information
- HGNC symbol
- YPEL3
- Aliases
- MGC10500
- Common name
- yippee like 3
- Entrez Id
- 83719
- Description
YPEL3 Ontologies
- Gene Ontology
-
Process: GO:2000774; positive regulation of cellular senescence
Cellular component: GO:5634; nucleus
GO:5730; nucleolus
Function: GO:46872; metal ion binding
Homologs of YPEL3 in Model Organisms
In other databases
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as MOH1
External links
- OMIM
- 609724
- Ensembl
- ENSG00000090238
- Entrez Gene
- 83719
- UniGene
- 513491
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- YPEL3
- GeneCards
- YPEL3