Cell Senescence Entries for YPEL3

Cell Types
Breast cancer
Cell Lines
MCF-7
Cancer Cell?
Yes
Method
Knockdown, Overexpression
Type of senescence
Stress-induced
Senescence Effect
Induces
Primary Reference
Tuttle et al. (2012) Novel senescence associated gene, YPEL3, is repressed by estrogen in ER+ mammary tumor cells and required for tamoxifen-induced cellular senescence. Int J Cancer 130(10)2291-9 (PubMed)

YPEL3 Gene Information

HGNC symbol
YPEL3 
Aliases
MGC10500 
Common name
yippee like 3 
Entrez Id
83719
Description

YPEL3 Ontologies

Gene Ontology
Process: GO:2000774; positive regulation of cellular senescence
Cellular component: GO:5634; nucleus
GO:5730; nucleolus
Function: GO:46872; metal ion binding
Show all GO terms

Homologs of YPEL3 in Model Organisms

Danio rerio
ypel3
Mus musculus
Ypel3
Rattus norvegicus
Ypel3
Saccharomyces cerevisiae
MOH1

In other databases

GenAge model organism genes
  • A homolog of this gene for Saccharomyces cerevisiae is present as MOH1

External links

OMIM
609724
Ensembl
ENSG00000090238
Entrez Gene
83719
UniGene
513491
1000 Genomes
1000 Genomes
HPRD
GenAtlas
YPEL3
GeneCards
YPEL3