Cell Senescence Entries for ZNF217
- Cell Types
- Mammary epithelial
- Cell Lines
- Primary cell
- Cancer Cell?
- No
- Method
- Overexpression
- Type of senescence
- Replicative
- Senescence Effect
- Inhibits
- Primary Reference
- Nonet et al. (2001) The ZNF217 gene amplified in breast cancers promotes immortalization of human mammary epithelial cells. Cancer Res 61(4)1250-4 (PubMed)
ZNF217 Gene Information
- HGNC symbol
- ZNF217
- Aliases
- ZABC1
- Common name
- zinc finger protein 217
- Entrez Id
- 7764
- Description
ZNF217 Ontologies
- Gene Ontology
-
Process: GO:45892; negative regulation of transcription, DNA-templated
GO:6355; regulation of transcription, DNA-templated
GO:122; negative regulation of transcription by RNA polymerase II
Cellular component: GO:5634; nucleus
GO:16607; nuclear speck
GO:5739; mitochondrion
GO:5654; nucleoplasm
GO:118; histone deacetylase complex
Show all GO termsFunction: GO:46872; metal ion binding
GO:3677; DNA binding
GO:5515; protein binding
GO:981; DNA-binding transcription factor activity, RNA polymerase II-specific
GO:978; RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:976; transcription cis-regulatory region binding
GO:1227; DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:3700; DNA-binding transcription factor activity
Homologs of ZNF217 in Model Organisms
- Danio rerio
- CABZ01070579.1
- Mus musculus
- Zfp217
- Rattus norvegicus
- Zfp217
External links
- OMIM
- 602967
- Ensembl
- ENSG00000171940
- Entrez Gene
- 7764
- UniGene
- 711564
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- ZNF217
- GeneCards
- ZNF217