Cell Senescence Entries for ATRAID

Cell Types
Retinal pigment epithelial
Cell Lines
ARPE-19
Cancer Cell?
Yes
Method
Overexpression
Type of senescence
Unclear
Senescence Effect
Induces
Primary Reference
Han et al. (2016) Apr3 accelerates the senescence of human retinal pigment epithelial cells. Mol Med Rep 13(4)3121-6 (PubMed)

ATRAID Gene Information

HGNC symbol
ATRAID 
Aliases
APR3; C2orf28; HSPC013; p18 
Common name
all-trans retinoic acid induced differentiation factor 
Entrez Id
51374
Description
This gene is thought to be involved in apoptosis, and may also be involved in hematopoietic development and differentiation. The use of alternative splice sites and promotors result in multiple transcript variants encoding different isoforms.[provided by RefSeq, Dec 2009].

ATRAID Ontologies

Gene Ontology
Process: GO:30154; cell differentiation
GO:10468; regulation of gene expression
GO:30501; positive regulation of bone mineralization
GO:45669; positive regulation of osteoblast differentiation
GO:1903363; negative regulation of cellular protein catabolic process
GO:33689; negative regulation of osteoblast proliferation
Cellular component: GO:5634; nucleus
GO:16020; membrane
GO:16021; integral component of membrane
GO:5886; plasma membrane
GO:5635; nuclear envelope
GO:48471; perinuclear region of cytoplasm
GO:43231; intracellular membrane-bounded organelle
GO:5765; lysosomal membrane
Function: GO:5515; protein binding
GO:3674; molecular_function
Hide GO terms

Homologs of ATRAID in Model Organisms

Danio rerio
atraid
Mus musculus
Atraid
Rattus norvegicus
Atraid

External links

OMIM
NA
Ensembl
ENSG00000138085
Entrez Gene
51374
UniGene
9527
1000 Genomes
1000 Genomes
HPRD
GenAtlas
ATRAID
GeneCards
ATRAID