Cell Senescence Entries for CDCA2
- Cell Types
- Lung fibroblast
- Cell Lines
- IMR-90
- Cancer Cell?
- No
- Method
- Overexpression
- Type of senescence
- Stress-induced
- Senescence Effect
- Inhibits
- Primary Reference
- Napolitano et al. (2015) Comparative analysis of gene expression data reveals novel targets of senescence-associated microRNAs. PLoS One 9(6)e98669 (PubMed)
CDCA2 Gene Information
- HGNC symbol
- CDCA2
- Aliases
- PPP1R81; Repo-Man
- Common name
- cell division cycle associated 2
- Entrez Id
- 157313
- Description
- This gene encodes a targeting subunit of the cell-cycle associated protein, protein phosphatase 1, with a role in targeting this protein to chromatin during anaphase. These two proteins comprise a phosphatase complex that is involved in nuclear envelope reformation and regulation of the DNA damage response. The encoded protein may also play a role in cancer progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015].
CDCA2 Ontologies
- Gene Ontology
-
Process: GO:7049; cell cycle
GO:51301; cell division
GO:35307; positive regulation of protein dephosphorylation
GO:7088; regulation of mitotic nuclear division
GO:51983; regulation of chromosome segregation
GO:7059; chromosome segregation
Cellular component: GO:5634; nucleus
GO:5654; nucleoplasm
GO:5829; cytosol
GO:5694; chromosome
Hide GO termsFunction:
Homologs of CDCA2 in Model Organisms
- Danio rerio
- si:ch211-244o22.2
- Mus musculus
- Cdca2
- Rattus norvegicus
- Cdca2
In other databases
- CellAge gene expression
- This gene is present as CDCA2
External links
- OMIM
- 618785
- Ensembl
- ENSG00000184661
- Entrez Gene
- 157313
- UniGene
- 33366
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- CDCA2
- GeneCards
- CDCA2