Cell Senescence Entries for CKAP2
- Cell Types
- Mammary fibroblast
- Cell Lines
- Primary cell
- Cancer Cell?
- No
- Method
- Knockdown
- Type of senescence
- Unclear
- Senescence Effect
- Inhibits
- Primary Reference
- Avelar et al. (2021) A multidimensional systems biology analysis of cellular senescence in aging and disease. Genome Biol 21(1)91 (PubMed)
CKAP2 Gene Information
- HGNC symbol
- CKAP2
- Aliases
- FLJ10749; LB1; se20-10; TMAP
- Common name
- cytoskeleton associated protein 2
- Entrez Id
- 26586
- Description
- This gene encodes a cytoskeleton-associated protein that stabalizes microtubules and plays a role in the regulation of cell division. The encoded protein is itself regulated through phosphorylation at multiple serine and threonine residues. There is a pseudogene of this gene on chromosome 14. Alternative splicing results in multiple transcript variations. [provided by RefSeq, Nov 2013].
CKAP2 Ontologies
- Gene Ontology
-
Process: GO:7049; cell cycle
GO:6915; apoptotic process
GO:7026; negative regulation of microtubule depolymerization
GO:45944; positive regulation of transcription by RNA polymerase II
GO:281; mitotic cytokinesis
Cellular component: GO:5737; cytoplasm
GO:5856; cytoskeleton
GO:5813; centrosome
GO:15630; microtubule cytoskeleton
GO:5874; microtubule
GO:72686; mitotic spindle
GO:5819; spindle
GO:922; spindle pole
Hide GO termsFunction:
Homologs of CKAP2 in Model Organisms
- Danio rerio
- si:ch211-266i6.3
- Mus musculus
- Ckap2
- Rattus norvegicus
- uncharacterized_F1LW
In other databases
- CellAge gene expression
- This gene is present as CKAP2
External links
- OMIM
- 611569
- Ensembl
- ENSG00000136108
- Entrez Gene
- 26586
- UniGene
- 594461
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- CKAP2
- GeneCards
- CKAP2