Cell Senescence Entries for CSNK1A1

Cell Types
Embryonic kidney, Retinal pigment epithelial
Cell Lines
HEK293T, HTERT-RPE1
Cancer Cell?
Yes
Method
Knockdown
Type of senescence
Unclear
Senescence Effect
Inhibits
Primary Reference
Lahtela et al. (2013) A high-content cellular senescence screen identifies candidate tumor suppressors, including EPHA3. Cell Cycle 12(4)625-34 (PubMed)

CSNK1A1 Gene Information

HGNC symbol
CSNK1A1 
Aliases
CK1; CK1a; CK1alpha; CKIa; CKIalpha 
Common name
casein kinase 1 alpha 1 
Entrez Id
1452
Description

CSNK1A1 Ontologies

Gene Ontology
Process: GO:6468; protein phosphorylation
GO:7049; cell cycle
GO:16310; phosphorylation
GO:51301; cell division
GO:16055; Wnt signaling pathway
GO:7165; signal transduction
GO:90090; negative regulation of canonical Wnt signaling pathway
GO:18105; peptidyl-serine phosphorylation
GO:7166; cell surface receptor signaling pathway
GO:45104; intermediate filament cytoskeleton organization
GO:7030; Golgi organization
GO:32436; positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:19082; viral protein processing
GO:1904424; regulation of GTP binding
GO:43161; proteasome-mediated ubiquitin-dependent protein catabolic process
Cellular component: GO:5634; nucleus
GO:5737; cytoplasm
GO:16607; nuclear speck
GO:16020; membrane
GO:5829; cytosol
GO:5856; cytoskeleton
GO:5694; chromosome
GO:42995; cell projection
GO:775; chromosome, centromeric region
GO:5815; microtubule organizing center
GO:5819; spindle
GO:776; kinetochore
GO:5813; centrosome
GO:36064; ciliary basal body
GO:5929; cilium
GO:5847; mRNA cleavage and polyadenylation specificity factor complex
GO:45095; keratin filament
GO:30877; beta-catenin destruction complex
Function: GO:166; nucleotide binding
GO:4672; protein kinase activity
GO:4674; protein serine/threonine kinase activity
GO:4712; protein serine/threonine/tyrosine kinase activity
GO:5524; ATP binding
GO:16301; kinase activity
GO:16740; transferase activity
GO:106310; protein serine kinase activity
GO:5515; protein binding
Hide GO terms

Homologs of CSNK1A1 in Model Organisms

Danio rerio
csnk1a1
Mus musculus
Csnk1a1
Rattus norvegicus
Csnk1a1
Saccharomyces cerevisiae
HRR25

External links

OMIM
600505
Ensembl
ENSG00000113712
Entrez Gene
1452
UniGene
712555
1000 Genomes
1000 Genomes
HPRD
GenAtlas
CSNK1A1
GeneCards
CSNK1A1