Cell Senescence Entries for DEPTOR
- Cell Types
- Myeloma
- Cell Lines
- MM.1S
- Cancer Cell?
- Yes
- Method
- Knockdown
- Type of senescence
- Unclear
- Senescence Effect
- Inhibits
- Primary Reference
- Yang et al. (2015) DEPTOR is linked to a TORC1-p21 survival proliferation pathway in multiple myeloma cells. Genes Cancer 5(11-12)407-19 (PubMed)
DEPTOR Gene Information
- HGNC symbol
- DEPTOR
- Aliases
- DEP.6; DEPDC6; FLJ12428
- Common name
- DEP domain containing MTOR interacting protein
- Entrez Id
- 64798
- Description
DEPTOR Ontologies
- Gene Ontology
-
Process: GO:35556; intracellular signal transduction
GO:32007; negative regulation of TOR signaling
GO:6469; negative regulation of protein kinase activity
GO:45792; negative regulation of cell size
GO:2001236; regulation of extrinsic apoptotic signaling pathway
GO:1903940; negative regulation of TORC2 signaling
GO:1904262; negative regulation of TORC1 signaling
Cellular component:
Hide GO termsFunction: GO:5515; protein binding
Homologs of DEPTOR in Model Organisms
In other databases
- LongevityMap
- This gene is present as DEPTOR
External links
- OMIM
- 612974
- Ensembl
- ENSG00000155792
- Entrez Gene
- 64798
- UniGene
- 112981
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- DEPTOR
- GeneCards
- DEPTOR