Cell Senescence Entries for EID3

Cell Types
Breast cancer
Cell Lines
MCF-7
Cancer Cell?
Yes
Method
Knockdown, Overexpression
Type of senescence
Stress-induced
Senescence Effect
Induces
Primary Reference
Wang et al. (2018) Upregulation of EID3 sensitizes breast cancer cells to ionizing radiation-induced cellular senescence. Biomed Pharmacother 107(2)606-614 (PubMed)

EID3 Gene Information

HGNC symbol
EID3 
Aliases
FLJ25832; NSE4B; NSMCE4B 
Common name
EP300 interacting inhibitor of differentiation 3 
Entrez Id
493861
Description

EID3 Ontologies

Gene Ontology
Process: GO:6281; DNA repair
GO:6974; cellular response to DNA damage stimulus
GO:6310; DNA recombination
GO:724; double-strand break repair via homologous recombination
GO:16925; protein sumoylation
GO:32204; regulation of telomere maintenance
Cellular component: GO:5634; nucleus
GO:5737; cytoplasm
GO:5654; nucleoplasm
GO:5730; nucleolus
GO:5694; chromosome
GO:781; chromosome, telomeric region
GO:30915; Smc5-Smc6 complex
Function: GO:5515; protein binding
Hide GO terms

Homologs of EID3 in Model Organisms

Danio rerio
nsmce4a
Mus musculus
Eid3
Rattus norvegicus
Eid3
Saccharomyces cerevisiae
NSE4

External links

OMIM
612986
Ensembl
ENSG00000255150
Entrez Gene
493861
UniGene
659857
1000 Genomes
1000 Genomes
HPRD
GenAtlas
EID3
GeneCards
EID3