Cell Senescence Entries for GKN1
- Cell Types
- Gastric cancer
- Cell Lines
- AGS, MKN1
- Cancer Cell?
- Yes
- Method
- Overexpression
- Type of senescence
- Replicative
- Senescence Effect
- Induces
- Primary Reference
- Yoon et al. (2015) Gastrokine 1 induces senescence and apoptosis through regulating telomere length in gastric cancer. Oncotarget 5(22)11695-708 (PubMed)
GKN1 Gene Information
- HGNC symbol
- GKN1
- Aliases
- AMP18; BRICD1; CA11
- Common name
- gastrokine 1
- Entrez Id
- 56287
- Description
- The protein encoded by this gene is found to be down-regulated in human gastric cancer tissue as compared to normal gastric mucosa. [provided by RefSeq, Jul 2008].
GKN1 Ontologies
- Gene Ontology
-
Process: GO:51781; positive regulation of cell division
GO:7586; digestion
GO:42127; regulation of cell population proliferation
Cellular component: GO:5794; Golgi apparatus
GO:5576; extracellular region
GO:5615; extracellular space
Hide GO termsFunction: GO:5515; protein binding
GO:3674; molecular_function
Homologs of GKN1 in Model Organisms
External links
- OMIM
- 606402
- Ensembl
- ENSG00000169605
- Entrez Gene
- 56287
- UniGene
- 69319
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- GKN1
- GeneCards
- GKN1