Cell Senescence Entries for GNG11
- Cell Types
- Lung fibroblast
- Cell Lines
- TIG-7
- Cancer Cell?
- No
- Method
- Knockout, Overexpression
- Type of senescence
- Stress-induced
- Senescence Effect
- Induces
- Primary Reference
- Hossain et al. (2007) G-protein gamma subunit GNG11 strongly regulates cellular senescence. Biochem Biophys Res Commun 351(3)645-50 (PubMed)
GNG11 Gene Information
- HGNC symbol
- GNG11
- Aliases
- GNGT11
- Common name
- G protein subunit gamma 11
- Entrez Id
- 2791
- Description
- This gene is a member of the guanine nucleotide-binding protein (G protein) gamma family and encodes a lipid-anchored, cell membrane protein. As a member of the heterotrimeric G protein complex, this protein plays a role in this transmembrane signaling system. This protein is also subject to carboxyl-terminal processing. Decreased expression of this gene is associated with splenic marginal zone lymphomas. [provided by RefSeq, Jul 2008].
GNG11 Ontologies
- Gene Ontology
-
Process: GO:7186; G protein-coupled receptor signaling pathway
GO:7165; signal transduction
Cellular component: GO:16020; membrane
GO:5886; plasma membrane
GO:5834; heterotrimeric G-protein complex
Hide GO termsFunction: GO:5515; protein binding
GO:31681; G-protein beta-subunit binding
GO:3924; GTPase activity
Homologs of GNG11 in Model Organisms
- Caenorhabditis elegans
- gpc-1
- Danio rerio
- gngt1
- Drosophila melanogaster
- Ggamma1
- Mus musculus
- Gng11
- Rattus norvegicus
- Gng11
In other databases
- GenAge model organism genes
- A homolog of this gene for Caenorhabditis elegans is present as gpc-1
External links
- OMIM
- 604390
- Ensembl
- ENSG00000127920
- Entrez Gene
- 2791
- UniGene
- 83381
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- GNG11
- GeneCards
- GNG11