Cell Senescence Entries for HAUS4

Cell Types
Mammary fibroblast
Cell Lines
Primary cell
Cancer Cell?
No
Method
Knockdown
Type of senescence
Unclear
Senescence Effect
Inhibits
Primary Reference
Avelar et al. (2021) A multidimensional systems biology analysis of cellular senescence in aging and disease. Genome Biol 21(1)91 (PubMed)

HAUS4 Gene Information

HGNC symbol
HAUS4 
Aliases
C14orf94; FLJ20424 
Common name
HAUS augmin like complex subunit 4 
Entrez Id
54930
Description
This gene encodes a subunit of the centrosome complex termed the human augmin complex. The encoded protein localizes to the spindle microtubules and may play a role in mitotic spindle assembly and maintenance of centrosome integrity during cell division. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009].

HAUS4 Ontologies

Gene Ontology
Process: GO:7049; cell cycle
GO:51301; cell division
GO:7098; centrosome cycle
GO:51225; spindle assembly
Cellular component: GO:5737; cytoplasm
GO:5856; cytoskeleton
GO:5874; microtubule
GO:5815; microtubule organizing center
GO:5819; spindle
GO:70652; HAUS complex
GO:5813; centrosome
GO:5829; cytosol
GO:1990498; mitotic spindle microtubule
Function: GO:5515; protein binding
GO:3674; molecular_function
GO:51011; microtubule minus-end binding
Hide GO terms

Homologs of HAUS4 in Model Organisms

Danio rerio
haus4
Mus musculus
Haus4
Rattus norvegicus
Haus4

In other databases

CellAge gene expression
  • This gene is present as HAUS4

External links

OMIM
613431
Ensembl
ENSG00000092036
Entrez Gene
54930
UniGene
727321
1000 Genomes
1000 Genomes
HPRD
GenAtlas
HAUS4
GeneCards
HAUS4