Cell Senescence Entries for HSPA2

Cell Types
Cervical cancer
Cell Lines
HeLa
Cancer Cell?
Yes
Method
Knockdown
Type of senescence
Unclear
Senescence Effect
Inhibits
Primary Reference
Rohde et al. (2005) Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms. Genes Dev 19(5)570-82 (PubMed)

HSPA2 Gene Information

HGNC symbol
HSPA2 
Aliases
 
Common name
heat shock protein family A (Hsp70) member 2 
Entrez Id
3306
Description

HSPA2 Ontologies

Gene Ontology
Process: GO:30154; cell differentiation
GO:9409; response to cold
GO:9408; response to heat
GO:7283; spermatogenesis
GO:16192; vesicle-mediated transport
GO:6986; response to unfolded protein
GO:42026; protein refolding
GO:90084; negative regulation of inclusion body assembly
GO:51085; chaperone cofactor-dependent protein refolding
GO:34620; cellular response to unfolded protein
GO:7140; male meiotic nuclear division
GO:7286; spermatid development
GO:1934; positive regulation of protein phosphorylation
GO:7141; male meiosis I
GO:10971; positive regulation of G2/M transition of mitotic cell cycle
GO:32781; positive regulation of ATPase activity
GO:70194; synaptonemal complex disassembly
GO:1901896; positive regulation of ATPase-coupled calcium transmembrane transporter activity
Cellular component: GO:5634; nucleus
GO:5737; cytoplasm
GO:16020; membrane
GO:5856; cytoskeleton
GO:5829; cytosol
GO:5819; spindle
GO:5886; plasma membrane
GO:70062; extracellular exosome
GO:72562; blood microparticle
GO:36128; CatSper complex
GO:72687; meiotic spindle
GO:795; synaptonemal complex
GO:1673; male germ cell nucleus
GO:9986; cell surface
Function: GO:166; nucleotide binding
GO:5524; ATP binding
GO:5515; protein binding
GO:16887; ATP hydrolysis activity
GO:51082; unfolded protein binding
GO:19899; enzyme binding
GO:44183; protein folding chaperone
GO:97718; disordered domain specific binding
GO:31072; heat shock protein binding
GO:51787; misfolded protein binding
GO:48156; tau protein binding
GO:51087; chaperone binding
GO:51861; glycolipid binding
Hide GO terms

Homologs of HSPA2 in Model Organisms

Mus musculus
Hspa2
Rattus norvegicus
Hspa2

In other databases

CellAge gene expression
  • This gene is present as HSPA2

External links

OMIM
140560
Ensembl
ENSG00000126803
Entrez Gene
3306
UniGene
432648
1000 Genomes
1000 Genomes
HPRD
GenAtlas
HSPA2
GeneCards
HSPA2