Cell Senescence Entries for JUNB

Cell Types
Prostate cancer
Cell Lines
Primary cell
Cancer Cell?
Yes
Method
Knockdown
Type of senescence
Unclear
Senescence Effect
Induces
Primary Reference
Konishi et al. (2008) Function of JunB in transient amplifying cell senescence and progression of human prostate cancer. Clin Cancer Res 14(14)4408-16 (PubMed)

JUNB Gene Information

HGNC symbol
JUNB 
Aliases
 
Common name
JunB proto-oncogene, AP-1 transcription factor subunit 
Entrez Id
3726
Description

JUNB Ontologies

Gene Ontology
Process: GO:6355; regulation of transcription, DNA-templated
GO:6357; regulation of transcription by RNA polymerase II
GO:51726; regulation of cell cycle
GO:42127; regulation of cell population proliferation
GO:45944; positive regulation of transcription by RNA polymerase II
GO:1570; vasculogenesis
GO:1649; osteoblast differentiation
GO:1701; in utero embryonic development
GO:1829; trophectodermal cell differentiation
GO:30316; osteoclast differentiation
GO:33687; osteoblast proliferation
GO:45597; positive regulation of cell differentiation
GO:46697; decidualization
GO:60136; embryonic process involved in female pregnancy
GO:60716; labyrinthine layer blood vessel development
GO:71277; cellular response to calcium ion
GO:140467; integrated stress response signaling
GO:2000319; regulation of T-helper 17 cell differentiation
Cellular component: GO:5634; nucleus
GO:5654; nucleoplasm
GO:785; chromatin
GO:5667; transcription regulator complex
GO:90575; RNA polymerase II transcription regulator complex
GO:35976; transcription factor AP-1 complex
Function: GO:3677; DNA binding
GO:3700; DNA-binding transcription factor activity
GO:5515; protein binding
GO:981; DNA-binding transcription factor activity, RNA polymerase II-specific
GO:978; RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:1990837; sequence-specific double-stranded DNA binding
GO:3690; double-stranded DNA binding
GO:977; RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:1228; DNA-binding transcription activator activity, RNA polymerase II-specific
Hide GO terms

Homologs of JUNB in Model Organisms

Danio rerio
junbb
Drosophila melanogaster
Jra
Mus musculus
Junb
Rattus norvegicus
Junb

External links

OMIM
165161
Ensembl
ENSG00000171223
Entrez Gene
3726
UniGene
25292
1000 Genomes
1000 Genomes
HPRD
GenAtlas
JUNB
GeneCards
JUNB