Cell Senescence Entries for NUAK1
- Cell Types
- Lung fibroblast
- Cell Lines
- WI-38
- Cancer Cell?
- No
- Method
- Knockout, Overexpression
- Type of senescence
- Unclear
- Senescence Effect
- Induces
- Primary Reference
- Humbert et al. (2010) Regulation of ploidy and senescence by the AMPK-related kinase NUAK1. EMBO J 29(2)376-86 (PubMed)
NUAK1 Gene Information
- HGNC symbol
- NUAK1
- Aliases
- ARK5; KIAA0537
- Common name
- NUAK family kinase 1
- Entrez Id
- 9891
- Description
NUAK1 Ontologies
- Gene Ontology
-
Process: GO:6468; protein phosphorylation
GO:16310; phosphorylation
GO:7155; cell adhesion
GO:6974; cellular response to DNA damage stimulus
GO:42127; regulation of cell population proliferation
GO:35556; intracellular signal transduction
GO:42149; cellular response to glucose starvation
GO:30155; regulation of cell adhesion
GO:1901796; regulation of signal transduction by p53 class mediator
GO:2000772; regulation of cellular senescence
GO:35507; regulation of myosin-light-chain-phosphatase activity
Cellular component: GO:5634; nucleus
GO:5737; cytoplasm
GO:5654; nucleoplasm
GO:1650; fibrillar center
GO:15630; microtubule cytoskeleton
Hide GO termsFunction: GO:46872; metal ion binding
GO:166; nucleotide binding
GO:4672; protein kinase activity
GO:4674; protein serine/threonine kinase activity
GO:4712; protein serine/threonine/tyrosine kinase activity
GO:5524; ATP binding
GO:16301; kinase activity
GO:16740; transferase activity
GO:106310; protein serine kinase activity
GO:5515; protein binding
GO:2039; p53 binding
Homologs of NUAK1 in Model Organisms
- Danio rerio
- si:dkey-261e22.1
- Mus musculus
- Nuak1
- Rattus norvegicus
- Nuak1
In other databases
- CellAge gene expression
- This gene is present as NUAK1
External links
- OMIM
- 608130
- Ensembl
- ENSG00000074590
- Entrez Gene
- 9891
- UniGene
- 524692
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- NUAK1
- GeneCards
- NUAK1