Cell Senescence Entries for NUAK2

Cell Types
Melanoma
Cell Lines
C32
Cancer Cell?
Yes
Method
Knockdown
Type of senescence
Oncogene-induced
Senescence Effect
Inhibits
Primary Reference
Namiki et al. (2011) AMP kinase-related kinase NUAK2 affects tumor growth, migration, and clinical outcome of human melanoma. Proc Natl Acad Sci U S A 108(16)6597-602 (PubMed)

NUAK2 Gene Information

HGNC symbol
NUAK2 
Aliases
FLJ90349; SNARK 
Common name
NUAK family kinase 2 
Entrez Id
81788
Description

NUAK2 Ontologies

Gene Ontology
Process: GO:6468; protein phosphorylation
GO:16310; phosphorylation
GO:43066; negative regulation of apoptotic process
GO:30036; actin cytoskeleton organization
GO:6915; apoptotic process
GO:35556; intracellular signal transduction
GO:42149; cellular response to glucose starvation
Cellular component: GO:5737; cytoplasm
Function: GO:46872; metal ion binding
GO:166; nucleotide binding
GO:4672; protein kinase activity
GO:4674; protein serine/threonine kinase activity
GO:4712; protein serine/threonine/tyrosine kinase activity
GO:5524; ATP binding
GO:16301; kinase activity
GO:16740; transferase activity
GO:106310; protein serine kinase activity
GO:5515; protein binding
GO:287; magnesium ion binding
Hide GO terms

Homologs of NUAK2 in Model Organisms

Danio rerio
nuak2
Mus musculus
Nuak2
Rattus norvegicus
Nuak2

External links

OMIM
608131
Ensembl
ENSG00000163545
Entrez Gene
81788
UniGene
497512
1000 Genomes
1000 Genomes
HPRD
GenAtlas
NUAK2
GeneCards
NUAK2