Cell Senescence Entries for RPS9
- Cell Types
- Osteosarcoma
- Cell Lines
- U2OS
- Cancer Cell?
- Yes
- Method
- Knockdown
- Type of senescence
- Unclear
- Senescence Effect
- Inhibits
- Primary Reference
- Lindström et al. (2011) Silencing of ribosomal protein S9 elicits a multitude of cellular responses inhibiting the growth of cancer cells subsequent to p53 activation. PLoS One 5(3)e9578 (PubMed)
RPS9 Gene Information
- HGNC symbol
- RPS9
- Aliases
- S9
- Common name
- ribosomal protein S9
- Entrez Id
- 6203
- Description
- Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S4P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, multiple processed pseudogenes derived from this gene are dispersed through the genome. [provided by RefSeq, Jul 2008].
RPS9 Ontologies
- Gene Ontology
-
Process: GO:6412; translation
GO:8284; positive regulation of cell population proliferation
GO:2181; cytoplasmic translation
GO:45903; positive regulation of translational fidelity
Cellular component: GO:5634; nucleus
GO:5737; cytoplasm
GO:16020; membrane
GO:110165; cellular anatomical entity
GO:5840; ribosome
GO:5925; focal adhesion
GO:5730; nucleolus
GO:15935; small ribosomal subunit
GO:1990904; ribonucleoprotein complex
GO:22627; cytosolic small ribosomal subunit
GO:5654; nucleoplasm
GO:5829; cytosol
GO:70062; extracellular exosome
GO:22626; cytosolic ribosome
GO:45202; synapse
Hide GO termsFunction: GO:3723; RNA binding
GO:3735; structural constituent of ribosome
GO:5515; protein binding
GO:19843; rRNA binding
GO:45182; translation regulator activity
Homologs of RPS9 in Model Organisms
- Caenorhabditis elegans
- rps-9
- Danio rerio
- rps9
- Drosophila melanogaster
- RpS9
- Mus musculus
- Rps9
- Rattus norvegicus
- Rps9
- Saccharomyces cerevisiae
- RPS9A
- Schizosaccharomyces pombe
- rps9a
In other databases
- CellAge gene expression
- This gene is present as RPS9
External links
- OMIM
- 603631
- Ensembl
- ENSG00000170889
- Entrez Gene
- 6203
- UniGene
- 546288
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- RPS9
- GeneCards
- RPS9