Cell Senescence Entries for RRAS2
- Cell Types
- HUVEC
- Cell Lines
- Primary cell
- Cancer Cell?
- No
- Method
- Knockdown
- Type of senescence
- Unclear
- Senescence Effect
- Inhibits
- Primary Reference
- Chen et al. (2019) 3' UTR lengthening as a novel mechanism in regulating cellular senescence. Genome Res 13(2)117-26 (PubMed)
RRAS2 Gene Information
- HGNC symbol
- RRAS2
- Aliases
- TC21
- Common name
- RAS related 2
- Entrez Id
- 22800
- Description
- This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010].
RRAS2 Ontologies
- Gene Ontology
-
Process: GO:7165; signal transduction
GO:7265; Ras protein signal transduction
GO:1649; osteoblast differentiation
GO:1901214; regulation of neuron death
GO:30335; positive regulation of cell migration
Cellular component: GO:16020; membrane
GO:5794; Golgi apparatus
GO:5886; plasma membrane
GO:5925; focal adhesion
GO:139; Golgi membrane
GO:70062; extracellular exosome
GO:5783; endoplasmic reticulum
Hide GO termsFunction: GO:166; nucleotide binding
GO:16787; hydrolase activity
GO:3924; GTPase activity
GO:5525; GTP binding
GO:5515; protein binding
GO:19003; GDP binding
Homologs of RRAS2 in Model Organisms
External links
- OMIM
- 600098
- Ensembl
- ENSG00000133818
- Entrez Gene
- 22800
- UniGene
- 712835
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- RRAS2
- GeneCards
- RRAS2