Cell Senescence Entries for SPIN1

Cell Types
Cervical cancer
Cell Lines
HeLa
Cancer Cell?
Yes
Method
Overexpression
Type of senescence
Unclear
Senescence Effect
Induces
Primary Reference
Yuan et al. (2008) Overexpression of SPINDLIN1 induces cellular senescence, multinucleation and apoptosis. Gene 410(1)67-74 (PubMed)

SPIN1 Gene Information

HGNC symbol
SPIN1 
Aliases
SPIN; TDRD24 
Common name
spindlin 1 
Entrez Id
10927
Description

SPIN1 Ontologies

Gene Ontology
Process: GO:7049; cell cycle
GO:6325; chromatin organization
GO:16055; Wnt signaling pathway
GO:45893; positive regulation of transcription, DNA-templated
GO:7276; gamete generation
GO:51321; meiotic cell cycle
GO:30177; positive regulation of Wnt signaling pathway
GO:6355; regulation of transcription, DNA-templated
GO:9303; rRNA transcription
Cellular component: GO:5634; nucleus
GO:5654; nucleoplasm
GO:5829; cytosol
GO:31965; nuclear membrane
GO:5730; nucleolus
GO:5819; spindle
Function: GO:5515; protein binding
GO:35064; methylated histone binding
Hide GO terms

Homologs of SPIN1 in Model Organisms

Danio rerio
LOC792822
Mus musculus
Spin1
Rattus norvegicus
Spin1

External links

OMIM
609936
Ensembl
ENSG00000106723
Entrez Gene
10927
UniGene
146804
1000 Genomes
1000 Genomes
HPRD
GenAtlas
SPIN1
GeneCards
SPIN1