Cell Senescence Entries for SUPT5H
- Cell Types
- Cervical cancer
- Cell Lines
- HeLa
- Cancer Cell?
- Yes
- Method
- Knockout
- Type of senescence
- Oncogene-induced
- Senescence Effect
- Inhibits
- Primary Reference
- Komori et al. (2009) Role of human transcription elongation factor DSIF in the suppression of senescence and apoptosis. Genes Cells 14(3)343-54 (PubMed)
SUPT5H Gene Information
- HGNC symbol
- SUPT5H
- Aliases
- FLJ34157; SPT5; SPT5H
- Common name
- SPT5 homolog, DSIF elongation factor subunit
- Entrez Id
- 6829
- Description
SUPT5H Ontologies
- Gene Ontology
-
Process: GO:6355; regulation of transcription, DNA-templated
GO:6357; regulation of transcription by RNA polymerase II
GO:45944; positive regulation of transcription by RNA polymerase II
GO:122; negative regulation of transcription by RNA polymerase II
GO:6368; transcription elongation from RNA polymerase II promoter
GO:32784; regulation of DNA-templated transcription, elongation
GO:16239; positive regulation of macroautophagy
GO:32785; negative regulation of DNA-templated transcription, elongation
GO:32786; positive regulation of DNA-templated transcription, elongation
GO:1900364; negative regulation of mRNA polyadenylation
Cellular component: GO:5634; nucleus
GO:5654; nucleoplasm
GO:32044; DSIF complex
Hide GO termsFunction: GO:3723; RNA binding
GO:5515; protein binding
GO:19899; enzyme binding
GO:3729; mRNA binding
GO:46982; protein heterodimerization activity
GO:3682; chromatin binding
Homologs of SUPT5H in Model Organisms
- Caenorhabditis elegans
- spt-5
- Danio rerio
- supt5h
- Drosophila melanogaster
- Spt5
- Mus musculus
- Supt5h
- Rattus norvegicus
- Supt5h
- Saccharomyces cerevisiae
- SPT5
- Schizosaccharomyces pombe
- spt5
External links
- OMIM
- 602102
- Ensembl
- ENSG00000196235
- Entrez Gene
- 6829
- UniGene
- 631604
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- SUPT5H
- GeneCards
- SUPT5H