Cell Senescence Entries for TFG
- Cell Types
- Prostate cancer
- Cell Lines
- DU145, LNCaP, PC-3
- Cancer Cell?
- Yes
- Method
- Knockdown
- Type of senescence
- Unclear
- Senescence Effect
- Inhibits
- Primary Reference
- Endoh et al. (2012) Identification of phosphorylated proteins involved in the oncogenesis of prostate cancer via Pin1-proteomic analysis. Prostate 72(6)626-37 (PubMed)
TFG Gene Information
- HGNC symbol
- TFG
- Aliases
- FLJ36137; SPG57; TF6
- Common name
- trafficking from ER to golgi regulator
- Entrez Id
- 10342
- Description
- There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene. [provided by RefSeq, Sep 2010].
TFG Ontologies
- Gene Ontology
-
Process: GO:6888; endoplasmic reticulum to Golgi vesicle-mediated transport
GO:43123; positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:16192; vesicle-mediated transport
GO:48208; COPII vesicle coating
Cellular component: GO:5737; cytoplasm
GO:43231; intracellular membrane-bounded organelle
GO:5783; endoplasmic reticulum
GO:5829; cytosol
GO:70971; endoplasmic reticulum exit site
Hide GO termsFunction: GO:5515; protein binding
GO:42802; identical protein binding
Homologs of TFG in Model Organisms
External links
- OMIM
- 602498
- Ensembl
- ENSG00000114354
- Entrez Gene
- 10342
- UniGene
- 518123
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- TFG
- GeneCards
- TFG