Cell Senescence Entries for ULK3

Cell Types
Lung fibroblast
Cell Lines
IMR-90
Cancer Cell?
No
Method
Overexpression
Type of senescence
Unclear
Senescence Effect
Induces
Primary Reference
Young et al. (2009) Autophagy mediates the mitotic senescence transition. Genes Dev 23(7)798-803 (PubMed)

ULK3 Gene Information

HGNC symbol
ULK3 
Aliases
DKFZP434C131; FLJ90566 
Common name
unc-51 like kinase 3 
Entrez Id
25989
Description

ULK3 Ontologies

Gene Ontology
Process: GO:6914; autophagy
GO:6468; protein phosphorylation
GO:16310; phosphorylation
GO:46777; protein autophosphorylation
GO:45880; positive regulation of smoothened signaling pathway
GO:18105; peptidyl-serine phosphorylation
GO:90398; cellular senescence
GO:45879; negative regulation of smoothened signaling pathway
GO:7224; smoothened signaling pathway
GO:72537; fibroblast activation
GO:1905037; autophagosome organization
Cellular component: GO:5737; cytoplasm
GO:407; phagophore assembly site
GO:97542; ciliary tip
GO:5776; autophagosome
Function: GO:166; nucleotide binding
GO:4672; protein kinase activity
GO:4674; protein serine/threonine kinase activity
GO:4712; protein serine/threonine/tyrosine kinase activity
GO:5524; ATP binding
GO:16301; kinase activity
GO:16740; transferase activity
GO:106310; protein serine kinase activity
GO:5515; protein binding
Hide GO terms

Homologs of ULK3 in Model Organisms

No homologs found

External links

OMIM
613472
Ensembl
ENSG00000140474
Entrez Gene
25989
UniGene
513034
1000 Genomes
1000 Genomes
HPRD
GenAtlas
ULK3
GeneCards
ULK3