Cell Senescence Entries for UTP6
- Cell Types
- Breast cancer
- Cell Lines
- MCF-7
- Cancer Cell?
- Yes
- Method
- Knockdown
- Type of senescence
- Oncogene-induced, Replicative
- Senescence Effect
- Inhibits
- Primary Reference
- Nishimura et al. (2015) Perturbation of ribosome biogenesis drives cells into senescence through 5S RNP-mediated p53 activation. Cell Rep 10(8)1310-23 (PubMed)
UTP6 Gene Information
- HGNC symbol
- UTP6
- Aliases
- C17orf40; HCA66
- Common name
- UTP6 small subunit processome component
- Entrez Id
- 55813
- Description
UTP6 Ontologies
- Gene Ontology
-
Process: GO:6396; RNA processing
GO:6364; rRNA processing
GO:462; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Cellular component: GO:5634; nucleus
GO:5730; nucleolus
GO:5694; chromosome
GO:32040; small-subunit processome
GO:34388; Pwp2p-containing subcomplex of 90S preribosome
GO:5654; nucleoplasm
Hide GO termsFunction: GO:5515; protein binding
GO:30515; snoRNA binding
Homologs of UTP6 in Model Organisms
External links
- OMIM
- NA
- Ensembl
- ENSG00000108651
- Entrez Gene
- 55813
- UniGene
- 589862
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- UTP6
- GeneCards
- UTP6