Cell Senescence Entries for CARF
- Cell Types
- Lung fibroblast
- Cell Lines
- MRC-5
- Cancer Cell?
- No
- Method
- Overexpression
- Type of senescence
- Replicative, Stress-induced
- Senescence Effect
- Induces
- Primary Reference
- Hasan et al. (2009) CARF Is a vital dual regulator of cellular senescence and apoptosis. J Biol Chem 284(3)1664-72 (PubMed)
CARF Gene Information
- HGNC symbol
- CARF
- Aliases
- ALS2CR8; FLJ21579; NYD-SP24
- Common name
- calcium responsive transcription factor
- Entrez Id
- 79800
- Description
CARF Ontologies
- Gene Ontology
-
Process: GO:61400; positive regulation of transcription from RNA polymerase II promoter in response to calcium ion
GO:6357; regulation of transcription by RNA polymerase II
GO:71277; cellular response to calcium ion
GO:35865; cellular response to potassium ion
GO:45944; positive regulation of transcription by RNA polymerase II
GO:51090; regulation of DNA-binding transcription factor activity
Cellular component: GO:5634; nucleus
GO:1652; granular component
Show all GO termsFunction: GO:3677; DNA binding
GO:3700; DNA-binding transcription factor activity
GO:5515; protein binding
GO:981; DNA-binding transcription factor activity, RNA polymerase II-specific
GO:978; RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:1228; DNA-binding transcription activator activity, RNA polymerase II-specific
Homologs of CARF in Model Organisms
External links
- OMIM
- 607586
- Ensembl
- ENSG00000138380
- Entrez Gene
- 79800
- UniGene
- 444982
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- CARF
- GeneCards
- CARF