Cell Senescence Entries for CDK18
- Cell Types
- Embryonic kidney, Lung fibroblast
- Cell Lines
- HEK293T, IMR-90, MRC-5
- Cancer Cell?
- No
- Method
- Overexpression
- Type of senescence
- Unclear
- Senescence Effect
- Induces
- Primary Reference
- Ferrand et al. (2016) Screening of a kinase library reveals novel pro-senescence kinases and their common NF-κB-dependent transcriptional program. Aging (Albany NY) 7(11)986-1003 (PubMed)
CDK18 Gene Information
- HGNC symbol
- CDK18
- Aliases
- PCTAIRE3; PCTK3
- Common name
- cyclin dependent kinase 18
- Entrez Id
- 5129
- Description
CDK18 Ontologies
- Gene Ontology
-
Process: GO:6468; protein phosphorylation
GO:16310; phosphorylation
GO:51726; regulation of cell cycle
GO:83; regulation of transcription involved in G1/S transition of mitotic cell cycle
Cellular component: GO:5634; nucleus
GO:5737; cytoplasm
GO:5575; cellular_component
Show all GO termsFunction: GO:166; nucleotide binding
GO:4672; protein kinase activity
GO:4674; protein serine/threonine kinase activity
GO:4712; protein serine/threonine/tyrosine kinase activity
GO:5524; ATP binding
GO:16301; kinase activity
GO:16740; transferase activity
GO:106310; protein serine kinase activity
GO:5515; protein binding
GO:4693; cyclin-dependent protein serine/threonine kinase activity
Homologs of CDK18 in Model Organisms
- Caenorhabditis elegans
- pct-1
- Danio rerio
- LOC100150007
- Mus musculus
- Cdk18
- Rattus norvegicus
- Cdk18
External links
- OMIM
- 169190
- Ensembl
- ENSG00000117266
- Entrez Gene
- 5129
- UniGene
- 445402
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- CDK18
- GeneCards
- CDK18