Cell Senescence Entries for CIP2A
- Cell Types
- Gastric cancer
- Cell Lines
- AGS, BGC-823, HGC-27, KATO-III
- Cancer Cell?
- Yes
- Method
- Knockdown
- Type of senescence
- Unclear
- Senescence Effect
- Inhibits
- Primary Reference
- Li et al. (2008) CIP2A is overexpressed in gastric cancer and its depletion leads to impaired clonogenicity, senescence, or differentiation of tumor cells. Clin Cancer Res 14(12)3722-8 (PubMed)
CIP2A Gene Information
- HGNC symbol
- CIP2A
- Aliases
- KIAA1524
- Common name
- cellular inhibitor of PP2A
- Entrez Id
- 57650
- Description
CIP2A Ontologies
- Gene Ontology
-
Process: Cellular component: GO:5737; cytoplasm
GO:16020; membrane
GO:16021; integral component of membrane
GO:5829; cytosol
GO:5886; plasma membrane
Show all GO termsFunction: GO:42803; protein homodimerization activity
GO:5515; protein binding
GO:45296; cadherin binding
Homologs of CIP2A in Model Organisms
- Danio rerio
- zgc:174160
- Drosophila melanogaster
- CG12702-RA
- Mus musculus
- Kiaa1524
- Rattus norvegicus
- RGD1310335
In other databases
- CellAge gene expression
- This gene is present as CIP2A
External links
- OMIM
- 610643
- Ensembl
- ENSG00000163507
- Entrez Gene
- 57650
- UniGene
- 591308
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- CIP2A
- GeneCards
- CIP2A