Cell Senescence Entries for DDIT4
- Cell Types
- Foreskin fibroblast
- Cell Lines
- BJ
- Cancer Cell?
- No
- Method
- Overexpression
- Type of senescence
- Replicative
- Senescence Effect
- Inhibits
- Primary Reference
- Kolesnichenko et al. (2012) Attenuation of TORC1 signaling delays replicative and oncogenic RAS-induced senescence. Cell Cycle 11(12)2391-401 (PubMed)
DDIT4 Gene Information
- HGNC symbol
- DDIT4
- Aliases
- Dig2; FLJ20500; REDD-1; REDD1; RTP801
- Common name
- DNA damage inducible transcript 4
- Entrez Id
- 54541
- Description
DDIT4 Ontologies
- Gene Ontology
-
Process: GO:6915; apoptotic process
GO:9968; negative regulation of signal transduction
GO:51607; defense response to virus
GO:1666; response to hypoxia
GO:32007; negative regulation of TOR signaling
GO:7420; brain development
GO:30182; neuron differentiation
GO:42771; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:1764; neuron migration
GO:32006; regulation of TOR signaling
GO:48011; neurotrophin TRK receptor signaling pathway
And 9 more GO terms Cellular component: GO:5737; cytoplasm
GO:5829; cytosol
GO:5739; mitochondrion
Show all GO termsFunction: GO:5515; protein binding
GO:71889; 14-3-3 protein binding
Homologs of DDIT4 in Model Organisms
External links
- OMIM
- 607729
- Ensembl
- ENSG00000168209
- Entrez Gene
- 54541
- UniGene
- 744875
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- DDIT4
- GeneCards
- DDIT4