Cell Senescence Entries for FOXQ1

Cell Types
Mesenchymal stem
Cell Lines
Primary cell
Cancer Cell?
No
Method
Overexpression
Type of senescence
Unclear
Senescence Effect
Inhibits
Primary Reference
Zhang et al. (2019) Overexpression of FOXQ1 enhances anti-senescence and migration effects of human umbilical cord mesenchymal stem cells in vitro and in vivo. Cell Tissue Res 373(2)379-393 (PubMed)

FOXQ1 Gene Information

HGNC symbol
FOXQ1 
Aliases
HFH1 
Common name
forkhead box Q1 
Entrez Id
94234
Description
FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called the forkhead or winged helix domain. FOX genes are involved in embryonic development, cell cycle regulation, tissue-specific gene expression, cell signaling, and tumorigenesis (Bieller et al., 2001 [PubMed 11747606]).[supplied by OMIM, May 2009].

FOXQ1 Ontologies

Gene Ontology
Process: GO:6355; regulation of transcription, DNA-templated
GO:6357; regulation of transcription by RNA polymerase II
GO:30154; cell differentiation
GO:9653; anatomical structure morphogenesis
GO:122; negative regulation of transcription by RNA polymerase II
GO:31069; hair follicle morphogenesis
GO:43524; negative regulation of neuron apoptotic process
Cellular component: GO:5634; nucleus
GO:785; chromatin
Function: GO:3677; DNA binding
GO:3700; DNA-binding transcription factor activity
GO:43565; sequence-specific DNA binding
GO:981; DNA-binding transcription factor activity, RNA polymerase II-specific
GO:978; RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:1990837; sequence-specific double-stranded DNA binding
GO:1227; DNA-binding transcription repressor activity, RNA polymerase II-specific
Hide GO terms

Homologs of FOXQ1 in Model Organisms

Danio rerio
foxq1a
Mus musculus
Foxq1
Rattus norvegicus
Foxq1

External links

OMIM
612788
Ensembl
ENSG00000164379
Entrez Gene
94234
UniGene
591352
1000 Genomes
1000 Genomes
HPRD
GenAtlas
FOXQ1
GeneCards
FOXQ1