Cell Senescence Entries for HAUS4
- Cell Types
- Mammary fibroblast
- Cell Lines
- Primary cell
- Cancer Cell?
- No
- Method
- Knockdown
- Type of senescence
- Unclear
- Senescence Effect
- Inhibits
- Primary Reference
- Avelar et al. (2021) A multidimensional systems biology analysis of cellular senescence in aging and disease. Genome Biol 21(1)91 (PubMed)
HAUS4 Gene Information
- HGNC symbol
- HAUS4
- Aliases
- C14orf94; FLJ20424
- Common name
- HAUS augmin like complex subunit 4
- Entrez Id
- 54930
- Description
- This gene encodes a subunit of the centrosome complex termed the human augmin complex. The encoded protein localizes to the spindle microtubules and may play a role in mitotic spindle assembly and maintenance of centrosome integrity during cell division. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009].
HAUS4 Ontologies
- Gene Ontology
-
Process: GO:7049; cell cycle
GO:51301; cell division
GO:7098; centrosome cycle
GO:51225; spindle assembly
Cellular component: GO:5737; cytoplasm
GO:5856; cytoskeleton
GO:5874; microtubule
GO:5815; microtubule organizing center
GO:5819; spindle
GO:70652; HAUS complex
GO:5813; centrosome
GO:5829; cytosol
GO:1990498; mitotic spindle microtubule
Function: GO:5515; protein binding
GO:3674; molecular_function
GO:51011; microtubule minus-end binding
Homologs of HAUS4 in Model Organisms
In other databases
- CellAge gene expression
- This gene is present as HAUS4
External links
- OMIM
- 613431
- Ensembl
- ENSG00000092036
- Entrez Gene
- 54930
- UniGene
- 727321
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- HAUS4
- GeneCards
- HAUS4