Cell Senescence Entries for KSR2

Cell Types
Embryonic kidney, Retinal pigment epithelial
Cell Lines
HEK293T, HTERT-RPE1
Cancer Cell?
Yes
Method
Knockdown
Type of senescence
Unclear
Senescence Effect
Unclear
Primary Reference
Lahtela et al. (2013) A high-content cellular senescence screen identifies candidate tumor suppressors, including EPHA3. Cell Cycle 12(4)625-34 (PubMed)

KSR2 Gene Information

HGNC symbol
KSR2 
Aliases
FLJ25965 
Common name
kinase suppressor of ras 2 
Entrez Id
283455
Description

KSR2 Ontologies

Gene Ontology
Process: GO:6468; protein phosphorylation
GO:16310; phosphorylation
GO:7165; signal transduction
GO:19722; calcium-mediated signaling
GO:120162; positive regulation of cold-induced thermogenesis
GO:7265; Ras protein signal transduction
GO:35556; intracellular signal transduction
Cellular component: GO:5737; cytoplasm
GO:16020; membrane
GO:5886; plasma membrane
GO:5829; cytosol
Function: GO:46872; metal ion binding
GO:166; nucleotide binding
GO:4672; protein kinase activity
GO:4674; protein serine/threonine kinase activity
GO:4712; protein serine/threonine/tyrosine kinase activity
GO:5524; ATP binding
GO:16301; kinase activity
GO:16740; transferase activity
GO:106310; protein serine kinase activity
GO:5515; protein binding
Show all GO terms

Homologs of KSR2 in Model Organisms

Danio rerio
ksr2
Mus musculus
Ksr2
Rattus norvegicus
Ksr2

External links

OMIM
610737
Ensembl
ENSG00000171435
Entrez Gene
283455
UniGene
375836
1000 Genomes
1000 Genomes
HPRD
GenAtlas
KSR2
GeneCards
KSR2