Cell Senescence Entries for MEOX1

Cell Types
Umbilical vein endothelial
Cell Lines
HUVEC
Cancer Cell?
No
Method
Overexpression
Type of senescence
Unclear
Senescence Effect
Induces
Primary Reference
Douville et al. (2012) Mechanisms of MEOX1 and MEOX2 regulation of the cyclin dependent kinase inhibitors p21 and p16 in vascular endothelial cells. PLoS One 6(12)e29099 (PubMed)

MEOX1 Gene Information

HGNC symbol
MEOX1 
Aliases
MOX1 
Common name
mesenchyme homeobox 1 
Entrez Id
4222
Description
This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the molecular signaling network regulating somite development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

MEOX1 Ontologies

Gene Ontology
Process: GO:6355; regulation of transcription, DNA-templated
GO:45944; positive regulation of transcription by RNA polymerase II
GO:6357; regulation of transcription by RNA polymerase II
GO:8150; biological_process
GO:7275; multicellular organism development
GO:60218; hematopoietic stem cell differentiation
GO:61053; somite development
GO:1757; somite specification
GO:61056; sclerotome development
Cellular component: GO:5634; nucleus
GO:5737; cytoplasm
GO:785; chromatin
Function: GO:3677; DNA binding
GO:3700; DNA-binding transcription factor activity
GO:981; DNA-binding transcription factor activity, RNA polymerase II-specific
GO:43565; sequence-specific DNA binding
GO:5515; protein binding
GO:978; RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:1990837; sequence-specific double-stranded DNA binding
GO:1228; DNA-binding transcription activator activity, RNA polymerase II-specific
GO:3682; chromatin binding
GO:71837; HMG box domain binding
Show all GO terms

Homologs of MEOX1 in Model Organisms

Danio rerio
meox1
Drosophila melanogaster
slou
Mus musculus
Meox1
Rattus norvegicus
Meox1

External links

OMIM
600147
Ensembl
ENSG00000005102
Entrez Gene
4222
UniGene
438
1000 Genomes
1000 Genomes
HPRD
GenAtlas
MEOX1
GeneCards
MEOX1