Cell Senescence Entries for MORF4L1

Cell Types
Foreskin fibroblast
Cell Lines
BJ
Cancer Cell?
No
Method
Knockout
Type of senescence
Stress-induced
Senescence Effect
Inhibits
Primary Reference
Liu et al. (2020) A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. Aging (Albany NY) 11(12)4011-4031 (PubMed)

MORF4L1 Gene Information

HGNC symbol
MORF4L1 
Aliases
Eaf3; HsT17725; MEAF3; MORFRG15; MRG15 
Common name
mortality factor 4 like 1 
Entrez Id
10933
Description

MORF4L1 Ontologies

Gene Ontology
Process: GO:6355; regulation of transcription, DNA-templated
GO:6325; chromatin organization
GO:6281; DNA repair
GO:6974; cellular response to DNA damage stimulus
GO:6310; DNA recombination
GO:40008; regulation of growth
GO:16573; histone acetylation
GO:43968; histone H2A acetylation
GO:43967; histone H4 acetylation
GO:45893; positive regulation of transcription, DNA-templated
GO:724; double-strand break repair via homologous recombination
And 7 more GO terms
Cellular component: GO:5634; nucleus
GO:16607; nuclear speck
GO:35267; NuA4 histone acetyltransferase complex
GO:16580; Sin3 complex
GO:5654; nucleoplasm
GO:123; histone acetyltransferase complex
GO:786; nucleosome
Function: GO:5515; protein binding
GO:47485; protein N-terminus binding
GO:3682; chromatin binding
Show all GO terms

Homologs of MORF4L1 in Model Organisms

Danio rerio
morf4l1
Mus musculus
Morf4l1
Rattus norvegicus
Morf4l1

External links

OMIM
607303
Ensembl
ENSG00000185787
Entrez Gene
10933
UniGene
374503
1000 Genomes
1000 Genomes
HPRD
GenAtlas
MORF4L1
GeneCards
MORF4L1