Cell Senescence Entries for NADK
- Cell Types
- Embryonic kidney, Lung fibroblast
- Cell Lines
- HEK293T, IMR-90, MRC-5
- Cancer Cell?
- No
- Method
- Overexpression
- Type of senescence
- Unclear
- Senescence Effect
- Induces
- Primary Reference
- Ferrand et al. (2016) Screening of a kinase library reveals novel pro-senescence kinases and their common NF-κB-dependent transcriptional program. Aging (Albany NY) 7(11)986-1003 (PubMed)
NADK Gene Information
- HGNC symbol
- NADK
- Aliases
- FLJ13052
- Common name
- NAD kinase
- Entrez Id
- 65220
- Description
- NADK catalyzes the transfer of a phosphate group from ATP to NAD to generate NADP, which in its reduced form acts as an electron donor for biosynthetic reactions (Lerner et al., 2001 [PubMed 11594753]).[supplied by OMIM, Mar 2008].
NADK Ontologies
- Gene Ontology
-
Process: GO:16310; phosphorylation
GO:19674; NAD metabolic process
GO:6741; NADP biosynthetic process
GO:46034; ATP metabolic process
Cellular component: GO:5829; cytosol
Show all GO termsFunction: GO:46872; metal ion binding
GO:166; nucleotide binding
GO:5524; ATP binding
GO:16301; kinase activity
GO:16740; transferase activity
GO:3951; NAD+ kinase activity
GO:16773; phosphotransferase activity, alcohol group as acceptor
GO:5515; protein binding
Homologs of NADK in Model Organisms
- Danio rerio
- nadkb
- Drosophila melanogaster
- CG6145
- Mus musculus
- Nadk
- Rattus norvegicus
- Nadk
- Saccharomyces cerevisiae
- UTR1
- Schizosaccharomyces pombe
- SPAC3H5.11
External links
- OMIM
- 611616
- Ensembl
- ENSG00000008130
- Entrez Gene
- 65220
- UniGene
- 731532
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- NADK
- GeneCards
- NADK