Cell Senescence Entries for NCAPH2

Cell Types
Lung fibroblast
Cell Lines
IMR-90
Cancer Cell?
No
Method
Mutation, Overexpression
Type of senescence
Oncogene-induced
Senescence Effect
Induces
Primary Reference
Yokoyama et al. (2016) A novel role for the condensin II complex in cellular senescence. Cell Cycle 14(13)2160-70 (PubMed)

NCAPH2 Gene Information

HGNC symbol
NCAPH2 
Aliases
384D8-2; CAP-H2; hCAP-H2 
Common name
non-SMC condensin II complex subunit H2 
Entrez Id
29781
Description
This gene encodes one of the non-SMC subunits of the condensin II complex. This complex plays an essential role in mitotic chromosome assembly. Alternate splicing of this gene results in multiple transcript variants.[provided by RefSeq, May 2010].

NCAPH2 Ontologies

Gene Ontology
Process: GO:30261; chromosome condensation
GO:7076; mitotic chromosome condensation
GO:1905821; positive regulation of chromosome condensation
GO:10032; meiotic chromosome condensation
GO:7143; female meiotic nuclear division
GO:33077; T cell differentiation in thymus
GO:51306; mitotic sister chromatid separation
GO:51309; female meiosis chromosome separation
GO:51984; positive regulation of chromosome segregation
GO:1905820; positive regulation of chromosome separation
Cellular component: GO:5634; nucleus
GO:16020; membrane
GO:5654; nucleoplasm
GO:45171; intercellular bridge
GO:5694; chromosome
GO:30054; cell junction
GO:796; condensin complex
GO:793; condensed chromosome
GO:794; condensed nuclear chromosome
Function: GO:5515; protein binding
GO:3682; chromatin binding
Show all GO terms

Homologs of NCAPH2 in Model Organisms

Caenorhabditis elegans
kle-2
Danio rerio
ncaph2
Mus musculus
Ncaph2
Rattus norvegicus
Ncaph2

External links

OMIM
611230
Ensembl
ENSG00000025770
Entrez Gene
29781
UniGene
730607
1000 Genomes
1000 Genomes
HPRD
GenAtlas
NCAPH2
GeneCards
NCAPH2