Cell Senescence Entries for POU3F1
- Cell Types
- Lung cancer
- Cell Lines
- H460
- Cancer Cell?
- Yes
- Method
- Knockdown
- Type of senescence
- Stress-induced
- Senescence Effect
- Induces
- Primary Reference
- Fionda et al. (2020) The POU-Domain Transcription Factor Oct-6/POU3F1 as a Regulator of Cellular Response to Genotoxic Stress. Cancers (Basel) 11(6)117-26 (PubMed)
POU3F1 Gene Information
- HGNC symbol
- POU3F1
- Aliases
- OCT6; OTF6; SCIP
- Common name
- POU class 3 homeobox 1
- Entrez Id
- 5453
- Description
POU3F1 Ontologies
- Gene Ontology
-
Process: GO:6355; regulation of transcription, DNA-templated
GO:6357; regulation of transcription by RNA polymerase II
GO:45893; positive regulation of transcription, DNA-templated
GO:7420; brain development
GO:10628; positive regulation of gene expression
GO:8366; axon ensheathment
GO:8544; epidermis development
GO:14044; Schwann cell development
GO:22011; myelination in peripheral nervous system
GO:30216; keratinocyte differentiation
GO:30900; forebrain development
And 2 more GO terms Cellular component: GO:5634; nucleus
GO:5654; nucleoplasm
GO:785; chromatin
GO:5667; transcription regulator complex
Show all GO termsFunction: GO:3677; DNA binding
GO:3700; DNA-binding transcription factor activity
GO:981; DNA-binding transcription factor activity, RNA polymerase II-specific
GO:978; RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:1990837; sequence-specific double-stranded DNA binding
GO:43565; sequence-specific DNA binding
Homologs of POU3F1 in Model Organisms
- Caenorhabditis elegans
- ceh-18
- Danio rerio
- pou3f1
- Drosophila melanogaster
- vvl
- Mus musculus
- Pou3f1
- Rattus norvegicus
- Pou3f1
In other databases
- GenAge model organism genes
- A homolog of this gene for Caenorhabditis elegans is present as ceh-18
External links
- OMIM
- 602479
- Ensembl
- ENSG00000185668
- Entrez Gene
- 5453
- UniGene
- 1837
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- POU3F1
- GeneCards
- POU3F1