Cell Senescence Entries for RACK1

Cell Types
Cervical cancer
Cell Lines
CaSki
Cancer Cell?
Yes
Method
Overexpression
Type of senescence
Unclear
Senescence Effect
Inhibits
Primary Reference
Liao et al. (2018) The receptor for activated protein kinase C promotes cell growth, invasion and migration in cervical cancer. Int J Oncol 51(5)1497-1507 (PubMed)

RACK1 Gene Information

HGNC symbol
RACK1 
Aliases
Gnb2-rs1; GNB2L1; H12.3 
Common name
receptor for activated C kinase 1 
Entrez Id
10399
Description

RACK1 Ontologies

Gene Ontology
Process: GO:7049; cell cycle
GO:16567; protein ubiquitination
GO:6915; apoptotic process
GO:6417; regulation of translation
GO:17148; negative regulation of translation
GO:1934; positive regulation of protein phosphorylation
GO:48511; rhythmic process
GO:43065; positive regulation of apoptotic process
GO:40008; regulation of growth
GO:10629; negative regulation of gene expression
GO:51726; regulation of cell cycle
And 32 more GO terms
Cellular component: GO:5634; nucleus
GO:5737; cytoplasm
GO:16020; membrane
GO:5654; nucleoplasm
GO:5829; cytosol
GO:5886; plasma membrane
GO:5739; mitochondrion
GO:5840; ribosome
GO:42995; cell projection
GO:30425; dendrite
GO:15935; small ribosomal subunit
And 12 more GO terms
Function: GO:3723; RNA binding
GO:5515; protein binding
GO:5102; signaling receptor binding
GO:43022; ribosome binding
GO:45296; cadherin binding
GO:51434; BH3 domain binding
GO:42169; SH2 domain binding
GO:60090; molecular adaptor activity
GO:8200; ion channel inhibitor activity
GO:19903; protein phosphatase binding
GO:42803; protein homodimerization activity
And 8 more GO terms
Show all GO terms

Homologs of RACK1 in Model Organisms

Caenorhabditis elegans
rack-1
Danio rerio
gnb2l1
Drosophila melanogaster
Rack1
Mus musculus
Gnb2l1
Rattus norvegicus
Gnb2l1
Saccharomyces cerevisiae
ASC1
Schizosaccharomyces pombe
rkp1

In other databases

GenAge model organism genes
  • A homolog of this gene for Caenorhabditis elegans is present as rack-1

External links

OMIM
176981
Ensembl
ENSG00000204628
Entrez Gene
10399
UniGene
5662
1000 Genomes
1000 Genomes
HPRD
GenAtlas
RACK1
GeneCards
RACK1