Cell Senescence Entries for RANBP9

Cell Types
Lung cancer
Cell Lines
A549, H460
Cancer Cell?
Yes
Method
Knockdown
Type of senescence
Stress-induced
Senescence Effect
Inhibits
Primary Reference
Palmieri et al. (2017) Ran Binding Protein 9 (RanBP9) is a novel mediator of cellular DNA damage response in lung cancer cells. Oncotarget 7(14)18371-83 (PubMed)

RANBP9 Gene Information

HGNC symbol
RANBP9 
Aliases
RanBPM 
Common name
RAN binding protein 9 
Entrez Id
10048
Description
This gene encodes a protein that binds RAN, a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The protein encoded by this gene has also been shown to interact with several other proteins, including met proto-oncogene, homeodomain interacting protein kinase 2, androgen receptor, and cyclin-dependent kinase 11. [provided by RefSeq, Jul 2008].

RANBP9 Ontologies

Gene Ontology
Process: GO:7166; cell surface receptor signaling pathway
GO:7010; cytoskeleton organization
GO:65003; protein-containing complex assembly
GO:1902993; positive regulation of amyloid precursor protein catabolic process
GO:7020; microtubule nucleation
GO:70373; negative regulation of ERK1 and ERK2 cascade
Cellular component: GO:5634; nucleus
GO:5737; cytoplasm
GO:16020; membrane
GO:5654; nucleoplasm
GO:5829; cytosol
GO:5886; plasma membrane
GO:16604; nuclear body
GO:5875; microtubule associated complex
GO:151; ubiquitin ligase complex
Function: GO:5515; protein binding
GO:19899; enzyme binding
GO:31267; small GTPase binding
Show all GO terms

Homologs of RANBP9 in Model Organisms

Caenorhabditis elegans
CELE_Y54E5A.7
Danio rerio
ranbp9
Mus musculus
Ranbp9
Rattus norvegicus
Ranbp9

In other databases

GenAge model organism genes
  • A homolog of this gene for Caenorhabditis elegans is present as Y54E5A.7

External links

OMIM
603854
Ensembl
ENSG00000010017
Entrez Gene
10048
UniGene
708182
1000 Genomes
1000 Genomes
HPRD
GenAtlas
RANBP9
GeneCards
RANBP9