Cell Senescence Entries for RBM38

Cell Types
Liver cancer
Cell Lines
Hep G2, SMMC-7721
Cancer Cell?
Yes
Method
Overexpression
Type of senescence
Unclear
Senescence Effect
Induces
Primary Reference
Ye et al. (2018) RBM38 plays a tumor-suppressor role via stabilizing the p53-mdm2 loop function in hepatocellular carcinoma. J Exp Clin Cancer Res 37(1)212 (PubMed)

RBM38 Gene Information

HGNC symbol
RBM38 
Aliases
dJ800J21.2; HSRNASEB; RNPC1; seb4B; SEB4D 
Common name
RNA binding motif protein 38 
Entrez Id
55544
Description

RBM38 Ontologies

Gene Ontology
Process: GO:6397; mRNA processing
GO:8380; RNA splicing
GO:7049; cell cycle
GO:30154; cell differentiation
GO:43484; regulation of RNA splicing
GO:51726; regulation of cell cycle
GO:8285; negative regulation of cell population proliferation
GO:6978; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:70935; 3'-UTR-mediated mRNA stabilization
GO:6977; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:10830; regulation of myotube differentiation
And 1 more GO terms
Cellular component: GO:5634; nucleus
GO:5737; cytoplasm
GO:5829; cytosol
Function: GO:3676; nucleic acid binding
GO:3723; RNA binding
GO:5515; protein binding
GO:3730; mRNA 3'-UTR binding
GO:3729; mRNA binding
Show all GO terms

Homologs of RBM38 in Model Organisms

Caenorhabditis elegans
sup-12
Mus musculus
Rbm38
Rattus norvegicus
Rbm38

In other databases

GenAge model organism genes
  • A homolog of this gene for Mus musculus is present as Rbm38

External links

OMIM
612428
Ensembl
ENSG00000132819
Entrez Gene
55544
UniGene
236361
1000 Genomes
1000 Genomes
HPRD
GenAtlas
RBM38
GeneCards
RBM38