Cell Senescence Entries for RRAD
- Cell Types
- Breast cancer, Gastric cancer, Prostate cancer
- Cell Lines
- DU145, LNCaP, MDA-MB-468, MKN74, PC-3, SNU-638, SNU-668
- Cancer Cell?
- Yes
- Method
- Knockdown, Overexpression
- Type of senescence
- Replicative, Stress-induced
- Senescence Effect
- Inhibits
- Primary Reference
- Lee et al. (2010) A novel senescence-evasion mechanism involving Grap2 and Cyclin D interacting protein inactivation by Ras associated with diabetes in cancer cells under doxorubicin treatment. Cancer Res 70(11)4357-65 (PubMed)
RRAD Gene Information
- HGNC symbol
- RRAD
- Aliases
- RAD; REM3
- Common name
- RRAD, Ras related glycolysis inhibitor and calcium channel regulator
- Entrez Id
- 6236
- Description
RRAD Ontologies
- Gene Ontology
-
Process: GO:1901841; regulation of high voltage-gated calcium channel activity
GO:1901842; negative regulation of high voltage-gated calcium channel activity
GO:7264; small GTPase mediated signal transduction
Cellular component: GO:16020; membrane
GO:5886; plasma membrane
GO:5829; cytosol
Show all GO termsFunction: GO:166; nucleotide binding
GO:3924; GTPase activity
GO:5525; GTP binding
GO:5515; protein binding
GO:5516; calmodulin binding
GO:5246; calcium channel regulator activity
Homologs of RRAD in Model Organisms
External links
- OMIM
- 179503
- Ensembl
- ENSG00000166592
- Entrez Gene
- 6236
- UniGene
- 1027
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- RRAD
- GeneCards
- RRAD