Cell Senescence Entries for SERPINB2
- Cell Types
- Lung fibroblast
- Cell Lines
- IMR-90
- Cancer Cell?
- No
- Method
- Overexpression
- Type of senescence
- Unclear
- Senescence Effect
- Induces
- Primary Reference
- Hsieh et al. (2018) The serine protease inhibitor serpinB2 binds and stabilizes p21 in senescent cells. J Cell Sci 130(19)3272-3281 (PubMed)
SERPINB2 Gene Information
- HGNC symbol
- SERPINB2
- Aliases
- HsT1201; PAI-2; PAI2; PLANH2
- Common name
- serpin family B member 2
- Entrez Id
- 5055
- Description
SERPINB2 Ontologies
- Gene Ontology
-
Process: GO:10951; negative regulation of endopeptidase activity
GO:43066; negative regulation of apoptotic process
GO:10466; negative regulation of peptidase activity
GO:42730; fibrinolysis
GO:42060; wound healing
Cellular component: GO:5615; extracellular space
GO:5737; cytoplasm
GO:5576; extracellular region
GO:5886; plasma membrane
GO:1533; cornified envelope
Show all GO termsFunction: GO:4867; serine-type endopeptidase inhibitor activity
GO:30414; peptidase inhibitor activity
Homologs of SERPINB2 in Model Organisms
In other databases
- CellAge gene expression
- This gene is present as SERPINB2
External links
- OMIM
- 173390
- Ensembl
- ENSG00000197632
- Entrez Gene
- 5055
- UniGene
- 594481
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- SERPINB2
- GeneCards
- SERPINB2