Cell Senescence Entries for SPIN1
- Cell Types
- Cervical cancer
- Cell Lines
- HeLa
- Cancer Cell?
- Yes
- Method
- Overexpression
- Type of senescence
- Unclear
- Senescence Effect
- Induces
- Primary Reference
- Yuan et al. (2008) Overexpression of SPINDLIN1 induces cellular senescence, multinucleation and apoptosis. Gene 410(1)67-74 (PubMed)
SPIN1 Gene Information
- HGNC symbol
- SPIN1
- Aliases
- SPIN; TDRD24
- Common name
- spindlin 1
- Entrez Id
- 10927
- Description
SPIN1 Ontologies
- Gene Ontology
-
Process: GO:7049; cell cycle
GO:6325; chromatin organization
GO:16055; Wnt signaling pathway
GO:45893; positive regulation of transcription, DNA-templated
GO:7276; gamete generation
GO:51321; meiotic cell cycle
GO:30177; positive regulation of Wnt signaling pathway
GO:6355; regulation of transcription, DNA-templated
GO:9303; rRNA transcription
Cellular component: GO:5634; nucleus
GO:5654; nucleoplasm
GO:5829; cytosol
GO:31965; nuclear membrane
GO:5730; nucleolus
GO:5819; spindle
Function: GO:5515; protein binding
GO:35064; methylated histone binding
Homologs of SPIN1 in Model Organisms
External links
- OMIM
- 609936
- Ensembl
- ENSG00000106723
- Entrez Gene
- 10927
- UniGene
- 146804
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- SPIN1
- GeneCards
- SPIN1