Cell Senescence Entries for STK32C
- Cell Types
- Embryonic kidney, Lung fibroblast
- Cell Lines
- HEK293T, IMR-90, MRC-5
- Cancer Cell?
- No
- Method
- Overexpression
- Type of senescence
- Unclear
- Senescence Effect
- Induces
- Primary Reference
- Ferrand et al. (2016) Screening of a kinase library reveals novel pro-senescence kinases and their common NF-κB-dependent transcriptional program. Aging (Albany NY) 7(11)986-1003 (PubMed)
STK32C Gene Information
- HGNC symbol
- STK32C
- Aliases
- MGC23665; PKE; YANK3
- Common name
- serine/threonine kinase 32C
- Entrez Id
- 282974
- Description
- The protein encoded by this gene is a member of the serine/threonine protein kinase family. It is thought that this family member is functional in brain due to its high expression levels there. DNA methylation differences have been found in this gene in monozygotic twins that are discordant for adolescent depression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].
STK32C Ontologies
- Gene Ontology
-
Process: GO:6468; protein phosphorylation
GO:16310; phosphorylation
GO:35556; intracellular signal transduction
GO:18105; peptidyl-serine phosphorylation
Cellular component:
Show all GO termsFunction: GO:46872; metal ion binding
GO:166; nucleotide binding
GO:4672; protein kinase activity
GO:4674; protein serine/threonine kinase activity
GO:4712; protein serine/threonine/tyrosine kinase activity
GO:5524; ATP binding
GO:16301; kinase activity
GO:16740; transferase activity
GO:106310; protein serine kinase activity
GO:5515; protein binding
Homologs of STK32C in Model Organisms
External links
- OMIM
- NA
- Ensembl
- ENSG00000165752
- Entrez Gene
- 282974
- UniGene
- 665362
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- STK32C
- GeneCards
- STK32C