Cell Senescence Entries for STK40

Cell Types
Embryonic kidney, Lung fibroblast
Cell Lines
HEK293T, IMR-90, MRC-5
Cancer Cell?
No
Method
Overexpression
Type of senescence
Unclear
Senescence Effect
Induces
Primary Reference
Ferrand et al. (2016) Screening of a kinase library reveals novel pro-senescence kinases and their common NF-κB-dependent transcriptional program. Aging (Albany NY) 7(11)986-1003 (PubMed)

STK40 Gene Information

HGNC symbol
STK40 
Aliases
MGC4796; SgK495 
Common name
serine/threonine kinase 40 
Entrez Id
83931
Description

STK40 Ontologies

Gene Ontology
Process: GO:6468; protein phosphorylation
GO:16310; phosphorylation
GO:3016; respiratory system process
GO:5977; glycogen metabolic process
GO:10468; regulation of gene expression
GO:30324; lung development
GO:35264; multicellular organism growth
GO:43066; negative regulation of apoptotic process
GO:43408; regulation of MAPK cascade
GO:48286; lung alveolus development
GO:60425; lung morphogenesis
And 1 more GO terms
Cellular component: GO:5634; nucleus
GO:5737; cytoplasm
GO:5654; nucleoplasm
GO:5829; cytosol
Function: GO:166; nucleotide binding
GO:4672; protein kinase activity
GO:4674; protein serine/threonine kinase activity
GO:4712; protein serine/threonine/tyrosine kinase activity
GO:5524; ATP binding
GO:16301; kinase activity
GO:16740; transferase activity
GO:106310; protein serine kinase activity
GO:5515; protein binding
Show all GO terms

Homologs of STK40 in Model Organisms

Danio rerio
stk40
Mus musculus
Stk40
Rattus norvegicus
Stk40

External links

OMIM
609437
Ensembl
ENSG00000196182
Entrez Gene
83931
UniGene
471768
1000 Genomes
1000 Genomes
HPRD
GenAtlas
STK40
GeneCards
STK40