Cell Senescence Entries for CRISPLD2

Cell Types
Foreskin fibroblast
Cell Lines
BJ
Cancer Cell?
No
Method
Knockout
Type of senescence
Stress-induced
Senescence Effect
Inhibits
Primary Reference
Liu et al. (2020) A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. Aging (Albany NY) 11(12)4011-4031 (PubMed)

CRISPLD2 Gene Information

HGNC symbol
CRISPLD2 
Aliases
DKFZP434B044; LCRISP2; LGL1 
Common name
cysteine rich secretory protein LCCL domain containing 2 
Entrez Id
83716
Description

CRISPLD2 Ontologies

Gene Ontology
Process: GO:30198; extracellular matrix organization
GO:30324; lung development
GO:60325; face morphogenesis
Cellular component: GO:5576; extracellular region
GO:5615; extracellular space
GO:31012; extracellular matrix
GO:70062; extracellular exosome
GO:34774; secretory granule lumen
GO:1904813; ficolin-1-rich granule lumen
GO:30133; transport vesicle
Function: GO:5539; glycosaminoglycan binding
GO:8201; heparin binding
Show all GO terms

Homologs of CRISPLD2 in Model Organisms

Danio rerio
LOC100535149
Mus musculus
Crispld2
Rattus norvegicus
Crispld2

External links

OMIM
612434
Ensembl
ENSG00000103196
Entrez Gene
83716
UniGene
617091
1000 Genomes
1000 Genomes
HPRD
GenAtlas
CRISPLD2
GeneCards
CRISPLD2