Cell Senescence Entries for ARID3A
- Cell Types
- Murine fibroblast
- Cell Lines
- Primary cell
- Cancer Cell?
- No
- Method
- Overexpression
- Type of senescence
- Oncogene-induced
- Senescence Effect
- Inhibits
- Primary Reference
- Peeper et al. (2002) A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence. Nat Cell Biol 4(2)148-53 (PubMed)
ARID3A Gene Information
- HGNC symbol
- ARID3A
- Aliases
- BRIGHT; DRIL1
- Common name
- AT-rich interaction domain 3A
- Entrez Id
- 1820
- Description
- This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008].
ARID3A Ontologies
- Gene Ontology
-
Process: GO:6357; regulation of transcription by RNA polymerase II
GO:6355; regulation of transcription, DNA-templated
GO:45944; positive regulation of transcription by RNA polymerase II
Cellular component: GO:5634; nucleus
GO:5737; cytoplasm
GO:5654; nucleoplasm
GO:5829; cytosol
GO:45121; membrane raft
Show all GO termsFunction: GO:3677; DNA binding
GO:5515; protein binding
GO:3682; chromatin binding
GO:3712; transcription coregulator activity
GO:42802; identical protein binding
Homologs of ARID3A in Model Organisms
External links
- OMIM
- 603265
- Ensembl
- ENSG00000116017
- Entrez Gene
- 1820
- UniGene
- 660769
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- ARID3A
- GeneCards
- ARID3A