GenAge entry for SSTR3 (Homo sapiens)
Gene name (HAGRID: 100)
- HGNC symbol
- SSTR3
- Aliases
- Common name
- somatostatin receptor 3
Potential relevance to the human ageing process
- Main reason for selection
- Entry selected based on evidence showing that the gene product to be a target of genes previously linked to ageing
- Description
The somatostatin (SST) receptor SSTR3 may play a role in the involution of the human thymus and other age-related pathologies [385]. It have been associated with melanoma [1683]. SSTR3 has not been directly related to ageing, but it could be part of signalling cascades related to ageing.
Cytogenetic information
- Cytogenetic band
- 22q13.1
- Location
- 37,204,237 bp to 37,212,376 bp
- Orientation
- Minus strand
Protein information
- Gene Ontology
-
Process: GO:0007187; G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007267; cell-cell signaling
GO:0007268; chemical synaptic transmission
GO:0007283; spermatogenesis
GO:0008285; negative regulation of cell proliferation
GO:0008628; hormone-mediated apoptotic signaling pathway
GO:0021549; cerebellum development
GO:0030900; forebrain development
GO:0038170; somatostatin signaling pathway
GO:0042594; response to starvation
GO:0071385; cellular response to glucocorticoid stimulus
GO:0071392; cellular response to estradiol stimulus
Cellular component: GO:0005737; cytoplasm
GO:0005886; plasma membrane
GO:0005887; integral component of plasma membrane
GO:0043005; neuron projection
GO:0060170; ciliary membrane
GO:0097730; non-motile cilium
Hide GO termsFunction: GO:0004994; somatostatin receptor activity
GO:0005102; receptor binding
GO:0005515; protein binding
GO:0042923; neuropeptide binding
Protein interactions and network
Retrieve sequences for SSTR3
Homologs in model organisms
In other databases
- LongevityMap
- This gene is present as SSTR3