Protein sequence for HAGRID 150 (SIRT1) for HAGRID 150 (SIRT1)

Gene information

HGNC symbolSIRT1
Common namesirtuin 1

GO protein functions

GO:0001046core promoter sequence-specific DNA binding
GO:0001077transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0002039p53 binding
GO:0003714transcription corepressor activity
GO:0003714transcription corepressor activity
GO:0003950NAD+ ADP-ribosyltransferase activity
GO:0004407histone deacetylase activity
GO:0004407histone deacetylase activity
GO:0005515protein binding
GO:0008022protein C-terminus binding
GO:0008134transcription factor binding
GO:0017136NAD-dependent histone deacetylase activity
GO:0019213deacetylase activity
GO:0019899enzyme binding
GO:0033558protein deacetylase activity
GO:0033558protein deacetylase activity
GO:0034979NAD-dependent protein deacetylase activity
GO:0034979NAD-dependent protein deacetylase activity
GO:0034979NAD-dependent protein deacetylase activity
GO:0035257nuclear hormone receptor binding
GO:0042393histone binding
GO:0042802identical protein binding
GO:0043398HLH domain binding
GO:0043422protein kinase B binding
GO:0043425bHLH transcription factor binding
GO:0046872metal ion binding
GO:0046969NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019mitogen-activated protein kinase binding
GO:0070403NAD+ binding
GO:1990254keratin filament binding

Protein sequence for HAGRID 150 (SIRT1)

Protein sequence for HAGRID 150 (SIRT1) source (RefSeq)NP_036370
Sequence length747 aa

Sequence

     1  MADEAALALQ PGGSPSAAGA DREAASSPAG EPLRKRPRRD GPGLERSPGE PGGAAPEREV
    61  PAAARGCPGA AAAALWREAE AEAAAAGGEQ EAQATAAAGE GDNGPGLQGP SREPPLADNL
   121  YDEDDDDEGE EEEEAAAAAI GYRDNLLFGD EIITNGFHSC ESDEEDRASH ASSSDWTPRP
   181  RIGPYTFVQQ HLMIGTDPRT ILKDLLPETI PPPELDDMTL WQIVINILSE PPKRKKRKDI
   241  NTIEDAVKLL QECKKIIVLT GAGVSVSCGI PDFRSRDGIY ARLAVDFPDL PDPQAMFDIE
   301  YFRKDPRPFF KFAKEIYPGQ FQPSLCHKFI ALSDKEGKLL RNYTQNIDTL EQVAGIQRII
   361  QCHGSFATAS CLICKYKVDC EAVRGDIFNQ VVPRCPRCPA DEPLAIMKPE IVFFGENLPE
   421  QFHRAMKYDK DEVDLLIVIG SSLKVRPVAL IPSSIPHEVP QILINREPLP HLHFDVELLG
   481  DCDVIINELC HRLGGEYAKL CCNPVKLSEI TEKPPRTQKE LAYLSELPPT PLHVSEDSSS
   541  PERTSPPDSS VIVTLLDQAA KSNDDLDVSE SKGCMEEKPQ EVQTSRNVES IAEQMENPDL
   601  KNVGSSTGEK NERTSVAGTV RKCWPNRVAK EQISRRLDGN QYLFLPPNRY IFHGAEVYSD
   661  SEDDVLSSSS CGSNSDSGTC QSPSLEEPME DESEIEEFYN GLEDEPDVPE RAGGAGFGTD
   721  GDDQEAINEA ISVKQEVTDM NYPSNKS
Download sequence as FASTA