Protein sequence for HAGRID 195 (APEX1) for HAGRID 195 (APEX1)

Gene information

HGNC symbolAPEX1
Common nameAPEX nuclease (multifunctional DNA repair enzyme) 1

GO protein functions

GO:0003677DNA binding
GO:0003684damaged DNA binding
GO:0003691double-stranded telomeric DNA binding
GO:0003713transcription coactivator activity
GO:0003714transcription corepressor activity
GO:0003906DNA-(apurinic or apyrimidinic site) lyase activity
GO:0003906DNA-(apurinic or apyrimidinic site) lyase activity
GO:0004519endonuclease activity
GO:0004520endodeoxyribonuclease activity
GO:0004523RNA-DNA hybrid ribonuclease activity
GO:0004528phosphodiesterase I activity
GO:0004844uracil DNA N-glycosylase activity
GO:0005515protein binding
GO:0008081phosphoric diester hydrolase activity
GO:0008309double-stranded DNA exodeoxyribonuclease activity
GO:0008311double-stranded DNA 3'-5' exodeoxyribonuclease activity
GO:00084083'-5' exonuclease activity
GO:00084083'-5' exonuclease activity
GO:0016491oxidoreductase activity
GO:0016890site-specific endodeoxyribonuclease activity, specific for altered base
GO:0031490chromatin DNA binding
GO:0032403protein complex binding
GO:0044822poly(A) RNA binding
GO:0046872metal ion binding
GO:0051059NF-kappaB binding

Protein sequence for HAGRID 195 (APEX1)

Protein sequence for HAGRID 195 (APEX1) source (RefSeq)NP_001632
Sequence length318 aa

Sequence

     1  MPKRGKKGAV AEDGDELRTE PEAKKSKTAA KKNDKEAAGE GPALYEDPPD QKTSPSGKPA
    61  TLKICSWNVD GLRAWIKKKG LDWVKEEAPD ILCLQETKCS ENKLPAELQE LPGLSHQYWS
   121  APSDKEGYSG VGLLSRQCPL KVSYGIGDEE HDQEGRVIVA EFDSFVLVTA YVPNAGRGLV
   181  RLEYRQRWDE AFRKFLKGLA SRKPLVLCGD LNVAHEEIDL RNPKGNKKNA GFTPQERQGF
   241  GELLQAVPLA DSFRHLYPNT PYAYTFWTYM MNARSKNVGW RLDYFLLSHS LLPALCDSKI
   301  RSKALGSDHC PITLYLAL
Download sequence as FASTA