Protein sequence for HAGRID 215 (JAK2) for HAGRID 215 (JAK2)

Gene information

HGNC symbolJAK2
Common nameJanus kinase 2

GO protein functions

GO:0004672protein kinase activity
GO:0004713protein tyrosine kinase activity
GO:0004713protein tyrosine kinase activity
GO:0004713protein tyrosine kinase activity
GO:0004713protein tyrosine kinase activity
GO:0004715non-membrane spanning protein tyrosine kinase activity
GO:0004715non-membrane spanning protein tyrosine kinase activity
GO:0005088Ras guanyl-nucleotide exchange factor activity
GO:0005102receptor binding
GO:0005131growth hormone receptor binding
GO:0005131growth hormone receptor binding
GO:0005143interleukin-12 receptor binding
GO:0005515protein binding
GO:0005524ATP binding
GO:0008022protein C-terminus binding
GO:0019901protein kinase binding
GO:0020037heme binding
GO:0031702type 1 angiotensin receptor binding
GO:0033130acetylcholine receptor binding
GO:0035401histone kinase activity (H3-Y41 specific)
GO:0042169SH2 domain binding
GO:0042393histone binding
GO:0043548phosphatidylinositol 3-kinase binding
GO:0043560insulin receptor substrate binding
GO:0046872metal ion binding
GO:0051428peptide hormone receptor binding

Protein sequence for HAGRID 215 (JAK2)

Protein sequence for HAGRID 215 (JAK2) source (RefSeq)NP_004963
Sequence length1132 aa

Sequence

     1  MGMACLTMTE MEGTSTSSIY QNGDISGNAN SMKQIDPVLQ VYLYHSLGKS EADYLTFPSG
    61  EYVAEEICIA ASKACGITPV YHNMFALMSE TERIWYPPNH VFHIDESTRH NVLYRIRFYF
   121  PRWYCSGSNR AYRHGISRGA EAPLLDDFVM SYLFAQWRHD FVHGWIKVPV THETQEECLG
   181  MAVLDMMRIA KENDQTPLAI YNSISYKTFL PKCIRAKIQD YHILTRKRIR YRFRRFIQQF
   241  SQCKATARNL KLKYLINLET LQSAFYTEKF EVKEPGSGPS GEEIFATIII TGNGGIQWSR
   301  GKHKESETLT EQDLQLYCDF PNIIDVSIKQ ANQEGSNESR VVTIHKQDGK NLEIELSSLR
   361  EALSFVSLID GYYRLTADAH HYLCKEVAPP AVLENIQSNC HGPISMDFAI SKLKKAGNQT
   421  GLYVLRCSPK DFNKYFLTFA VERENVIEYK HCLITKNENE EYNLSGTKKN FSSLKDLLNC
   481  YQMETVRSDN IIFQFTKCCP PKPKDKSNLL VFRTNGVSDV PTSPTLQRPT HMNQMVFHKI
   541  RNEDLIFNES LGQGTFTKIF KGVRREVGDY GQLHETEVLL KVLDKAHRNY SESFFEAASM
   601  MSKLSHKHLV LNYGVCVCGD ENILVQEFVK FGSLDTYLKK NKNCINILWK LEVAKQLAWA
   661  MHFLEENTLI HGNVCAKNIL LIREEDRKTG NPPFIKLSDP GISITVLPKD ILQERIPWVP
   721  PECIENPKNL NLATDKWSFG TTLWEICSGG DKPLSALDSQ RKLQFYEDRH QLPAPKWAEL
   781  ANLINNCMDY EPDFRPSFRA IIRDLNSLFT PDYELLTEND MLPNMRIGAL GFSGAFEDRD
   841  PTQFEERHLK FLQQLGKGNF GSVEMCRYDP LQDNTGEVVA VKKLQHSTEE HLRDFEREIE
   901  ILKSLQHDNI VKYKGVCYSA GRRNLKLIME YLPYGSLRDY LQKHKERIDH IKLLQYTSQI
   961  CKGMEYLGTK RYIHRDLATR NILVENENRV KIGDFGLTKV LPQDKEYYKV KEPGESPIFW
  1021  YAPESLTESK FSVASDVWSF GVVLYELFTY IEKSKSPPAE FMRMIGNDKQ GQMIVFHLIE
  1081  LLKNNGRLPR PDGCPDEIYM IMTECWNNNV NQRPSFRDLA LRVDQIRDNM AG
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