Protein sequence for HAGRID 224 (PSEN1) for HAGRID 224 (PSEN1)


Gene information

HGNC symbolPSEN1
Common namepresenilin 1

GO protein functions

GO:0004175endopeptidase activity
GO:0004190aspartic-type endopeptidase activity
GO:0005262calcium channel activity
GO:0005515protein binding
GO:0008013beta-catenin binding
GO:0030165PDZ domain binding
GO:0045296cadherin binding

Protein sequence for HAGRID 224 (PSEN1)

Protein sequence for HAGRID 224 (PSEN1) source (RefSeq)NP_000012
Sequence length467 aa

Sequence

     1  MTELPAPLSY FQNAQMSEDN HLSNTVRSQN DNRERQEHND RRSLGHPEPL SNGRPQGNSR
    61  QVVEQDEEED EELTLKYGAK HVIMLFVPVT LCMVVVVATI KSVSFYTRKD GQLIYTPFTE
   121  DTETVGQRAL HSILNAAIMI SVIVVMTILL VVLYKYRCYK VIHAWLIISS LLLLFFFSFI
   181  YLGEVFKTYN VAVDYITVAL LIWNFGVVGM ISIHWKGPLR LQQAYLIMIS ALMALVFIKY
   241  LPEWTAWLIL AVISVYDLVA VLCPKGPLRM LVETAQERNE TLFPALIYSS TMVWLVNMAE
   301  GDPEAQRRVS KNSKYNAEST ERESQDTVAE NDDGGFSEEW EAQRDSHLGP HRSTPESRAA
   361  VQELSSSILA GEDPEERGVK LGLGDFIFYS VLVGKASATA SGDWNTTIAC FVAILIGLCL
   421  TLLLLAIFKK ALPALPISIT FGLVFYFATD YLVQPFMDQL AFHQFYI 
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